Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...
Reexamination Certificate
2007-11-27
2007-11-27
Hui, San-ming (Department: 1617)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Heterocyclic carbon compounds containing a hetero ring...
C514S423000, C514S424000, C514S253090
Reexamination Certificate
active
10407551
ABSTRACT:
The present invention makes available methods and reagents for inhibiting aberrant growth states resulting from hedgehog gain-of-function, ptc loss-of-function or smoothened gain-of-function comprising contacting the cell with a hedgehog antagonist, such as a small molecule, in a sufficient amount to aberrant growth state, e.g., to agonize a normal ptc pathway or antagonize smoothened or hedgehog activity.
REFERENCES:
patent: 5756528 (1998-05-01), Anthony et al.
patent: 5817678 (1998-10-01), Kim et al.
patent: 5892038 (1999-04-01), Dolle, III et al.
patent: 6127366 (2000-10-01), Kim et al.
patent: 6552016 (2003-04-01), Baxter et al.
patent: WO 98/30576 (1998-07-01), None
patent: WO 98/33797 (1998-08-01), None
patent: WO 98/57933 (1998-12-01), None
patent: WO 00/74706 (2000-12-01), None
patent: WO 01/26644 (2001-04-01), None
Essawi et al., “Synthesis and Evaluation of 1- and 2-Substituted Fentanyl Analogues for Opioid Activity,” J. Med. Chem. 26(3):348-352 (1983).
Baxter Anthony David
Boyd Edward Andrew
Guicherit Oivin
Price Stephen
Rubin Lee L.
Curis, Inc.
Hui San-ming
Millen White Zelano & Branigan P.C.
LandOfFree
Mediators of hedgehog signaling pathways, compositions and... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Mediators of hedgehog signaling pathways, compositions and..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Mediators of hedgehog signaling pathways, compositions and... will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-3884918