Medetomidine preparations for transdermal administration

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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Details

424447, 424448, 424449, A61L 1544, A61K 970, A61F 1300, A61F 1302

Patent

active

054380677

ABSTRACT:
Salts of medetomidine and optically active enantiomers, thereof, particularly the d-enantiomer are disclosed. These salts may be used to regulate the rate of the transdermal administration of active drugs. The transdermal delivery system comprises a drug impermeable backing layer and an adhesive layer wherein the medetomidine is dispersed throughout the adhesive layer.

REFERENCES:
patent: 4783477 (1988-11-01), Lammintausta et al.
patent: 5124157 (1992-06-01), Colley et al.
patent: 5217718 (1993-06-01), Colley et al.

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