Meclofenamic acid topical pharmaceutical composition

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Radical -xh acid – or anhydride – acid halide or salt thereof...

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Details

514825, 514944, A61K 31195

Patent

active

046020403

ABSTRACT:
A clear gel and a cream pharmaceutical composition containing meclofenamic acid are disclosed. The clear gel composition is prepared by dissolving meclofenamic acid in polyethylene glycol monolaurate and polyethylene glycol lanolin oil and adding isopropyl alcohol with mixing and finally adding colloidal silicon dioxide with mixing. The cream composition is prepared by adding meclofenamic acid or the sodium salt thereof to an emulsion prepared by mixing a warm aqueous solution of sorbic acid with a melt of polyethylene glycol monostearate, glyceryl monostearate, caprylic and capric triglyceride and mineral oil.
The resulting compositions are indicated for the treatment of inflammation.

REFERENCES:
patent: 3313848 (1967-04-01), Scherrer et al.
patent: 4154833 (1979-05-01), Tauber et al.
patent: 4185100 (1980-01-01), Rovee et al.
patent: 4206220 (1980-06-01), Sloan

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