Mechanically-stable, readily-disintegratable tablets made of sma

Details Mechanically-stable, readily-disintegratable tablets made of sma Mechanically-stable, readily-disintegratable tablets made of sma

1992-06-26

1994-02-22

Michl, Paul R.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Tablets, lozenges, or pills

424499, 424480, 424482, 514781, 5147722, A61K 920

Patent

active

052885011

ABSTRACT:
The application discloses a process for the manufacture of mechanically-stable, readily-disintegratable tablets made of small preformed, preferably rounded, particles or pellets containing a high percentage of active ingredient in which--prior to compression--the particles are coated with an aqueous or aqueous/organic suspension containing water-soluble polyvinyl alcohol having an ester content of 19.4 to 6.7%, a disintegrant, and finely-divided cellulose, the remainder being excipients such as additional colloids, adjuvants, dyes, and/or flavors and the suspending liquid, and dried, the stable but readily-friable tablet product thus-produced, and a method of delivering an active ingredient by the employment of such a tablet for oral ingestion.

REFERENCES:
patent: Re33670 (1991-08-01), Maglio
patent: 2691619 (1954-10-01), Bavley et al.
patent: 2805977 (1957-09-01), Robinson et al.
patent: 4110431 (1978-08-01), Oita
patent: 4159345 (1979-06-01), Takev et al.
patent: 4460562 (1984-07-01), Keith et al.

Affiliated with

Also associated with

Rating

Mechanically-stable, readily-disintegratable tablets made of sma does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Mechanically-stable, readily-disintegratable tablets made of sma, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Mechanically-stable, readily-disintegratable tablets made of sma will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-169410