Mechanically sheared collagen implant material and method

Details Mechanically sheared collagen implant material and method Mechanically sheared collagen implant material and method

1985-03-22

1987-02-10

Apley, Richard J.

Prosthesis (i.e., artificial body members), parts thereof, or ai

Implantable prosthesis

623 15, 623 11, 623 66, 128DIG8, 128 92R, 128 92W, 128 92YG, 128 92YR, 514801, 514 21, A61F 210, A61F 228, A61K 3712

Patent

active

046421173

ABSTRACT:
An injectable collagen material composed of reconstituted, mechanically sheared atelopeptide collagen fibers. The material is prepared by passing reconstituted collagen fibers repeatedly through a rigid mesh screen, until a substantial reduction in fiber size and size-heterogeneity is achieved. The mechanically sheared fibers may be further crosslinked to improve implant characteristics.

REFERENCES:
patent: 2364244 (1944-12-01), Roberson
patent: 3894132 (1975-07-01), Daniel
patent: 3949073 (1976-04-01), Daniels et al.
patent: 4273705 (1981-06-01), Kato
patent: 4424208 (1984-01-01), Wallace et al.
Chem. Abst. #91:194484h; "Stru.-Mech. Prop of Con. Disp. of Collagen"; Khanukov et al., 1979.

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