Mechanically induced trapping of molecular interactions

Details Mechanically induced trapping of molecular interactions Mechanically induced trapping of molecular interactions

2007-01-26

2011-10-18

Lam, Ann (Department: 1641)

Chemistry: analytical and immunological testing

Involving an insoluble carrier for immobilizing immunochemicals

Reexamination Certificate

active

08039269

ABSTRACT:
The invention provides devices and methods for surface patterning the substrate of a microfluidic device, and for detection and analysis of interactions between molecules by mechanically trapping a molecular complex while substantially expelling solvent and unbound solute molecules. Examples of molecular complexes include protein-protein complexes and protein-nucleic acid complexes.

REFERENCES:
patent: 5556961 (1996-09-01), Foote et al.
patent: 5959098 (1999-09-01), Goldberg et al.
patent: 6572742 (2003-06-01), Cohen
patent: 6899137 (2005-05-01), Unger et al.
patent: 6960437 (2005-11-01), Enzelberger et al.
patent: 7143785 (2006-12-01), Maerkl et al.
patent: 2004/0007470 (2004-01-01), Smalley
patent: 2004/0072278 (2004-04-01), Chou et al.
patent: 2007/0248971 (2007-10-01), Maerkl et al.
patent: 2010/0154890 (2010-06-01), Maerkl et al.
patent: WO 2007/089587 (2007-08-01), None
PCT International Preliminary Examination Report of Jul. 29, 2008 for application PCT/US07/002176.
PCT Search Report mailed Apr. 24, 2008 for application PCT/US07/002176.
PCT Written Opinion mailed Apr. 24, 2008 for application PCT/US07/002176.
Van Dam, “Solvent-Resistant Elastomeric Mircofludic Devices and Applications, PhD Thesis”, California Institute of Technology, 2005.

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