Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Nitrogen containing other than solely as a nitrogen in an...
Patent
1996-03-29
1998-10-27
MacMillan, Keith D.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Nitrogen containing other than solely as a nitrogen in an...
530315, 5303092, 5303093, A61K 2500
Patent
active
058278931
ABSTRACT:
A pharmaceutical composition is provided which comprises vasopressin and an adrenergic agent in combination with a pharmaceutically acceptable carrier. The pharmaceutical composition is effective to increase arterial blood pressure so as to enhance arterial blood flow to the brain and heart when administered to a patient suffering from cardiac arrest. A method of treating a patient in cardiac arrest is also provided, which method comprises the administration of the pharmaceutical composition during the administration of CPR.
REFERENCES:
patent: 4693243 (1987-09-01), Buras
Todd J. Cohen et al., "Active Compression-Decompression," JAMA, 267, 2916, (1992).
Mickey S. Eisenberg et al., "Long-Term Survival After Out-of-Hospital Cardiac Arrest," NEJM, 306, 1340, (1982).
T.A. Fischer et al., "Curent Status Phosphodiesterase Inhibitors in the Treatment of Congestive Heart Failure," Drugs, 44, 928, (1992).
Karl H. Lindner et al., "Effect of Vasopressin on Hemodynamic Variables, Organ Blood Flow, and Acid-Base Status in a Pig Model of Cardiopulminary Resuscitation," Anesthesia & Analgesia, 77, 427, (1993).
Karl H. Lindner et al., "Release of Endogenous Vasopressors During and After Cardiopulmonary Resuscitation," Br. Heart J., 75, 145, (1996).
Karl H. Lindner et al., "Effects of Active Compression-Decompression Resuscitation on Myocardial and Cerebral Blood Flow in Pigs," Circulation, 88, 1254, (1993).
Karl H. Lindner et al., "Vasopressin Improves Vital Organ Blood Flow During Closed-Chest Cardiopulmonary Resuscitation in Pigs," Circulation, 91, 215, (1994).
Keith G. Lurie, "Active Compression-Decompression CPR: A Progress Report," Resuscitation, 28, 115, (1994).
James T. Niemann, "Cardiopulmonary Resuscitation," NEJM, 327, 1075, (1992).
Jeffrey B. Sack et al., "Survival from In-Hospital Cardiac Arrest with Interposed Abdominal Counterpulsation During Cardiopulmonary Resuscitation," JAMA, 267, 379, (1992).
Ian G. Stiell et al., "High-Dose Epinephrine in Adult Cardiac Arrest," NEJM, 327, 1045, (1992).
S.P. Woodhouse et al., "High Dose and Standard Dose Adrenaline Do Not Alter Survival, Compared with Placebo, in Cardiac Arrest," Resuscitation, 30, 243, (1995).
Lindner Karl
Lurie Keith G.
LandOfFree
Mechanical and pharmacological therapies to treat cardiac arrest does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Mechanical and pharmacological therapies to treat cardiac arrest, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Mechanical and pharmacological therapies to treat cardiac arrest will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-1614281