mecB

Details mecB mecB

1998-03-18

2000-09-26

Campell, Bruce R.

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Recombinant dna technique included in method of making a...

4353201, 435325, 4352523, 536 237, C12P 2106, C12N 1500, C12N 500, C12N 120, C07H 2104

Patent

active

061241199

ABSTRACT:
The invention provides mecB polypeptides and polynucleotides encoding mecB polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing mecB polypeptides to screen for antibacterial compounds.

REFERENCES:
Min Dong Song: "Studies on the expression Mechanism of Beta-Lactam resistance in staphylococcus aureus" Korean Biochemical Journal, vol. 25, No. 4, 1992, pp. 342-346.
Corinne Rouquette, et al: "Identification of a CIpC ATPase required for stress tolerance and in vivo survival of Listeria monocytogenes" Molecular Biology, vol. 21, No. 5, Sep. 1996, pp. 977-987.
Tarek Msadek, et al: "MecB of Bacillus subtilis, a member of the CIpc ATPase family, is a pleiotropic regulator controlling competence gene expression and growth at high temperature" Proceedings of the National Academy of Sciences of USA, vol. 91, No. 13, Jun. 21, 1994, pp. 5788-5792.
EP search report from corresponding European patent application No. 98306683.8.
SwissProt Submission, Accession No. P37571, Direct Submission.

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