Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...
Patent
1990-05-23
1993-02-16
Kepplinger, Esther L.
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving antigen-antibody binding, specific binding protein...
436 63, 436518, 436811, G01N 33567
Patent
active
051870630
ABSTRACT:
The invention pertains to the dystrophin-glycoprotein complex of mammalian skeletal muscle and a method of isolating said complex. The components of the complex and methods of separating and isolating said components also pertain to the invention. In addition, the invention further relates to a method of diagnosing muscular dystrophy by detecting and quantifying the loss of a non-dystrophin component of the dystrophin-glycoprotein complex with said loss being indicative of muscular dystrophy.
REFERENCES:
patent: 4912202 (1990-03-01), Campbell et al.
Sevier et al., Clin. Chem. 27: 1797-1806, 1981.
Hoffman, E. P., et al., Cell, 51: 919-928 (1987).
Knudson, C. M., et al., J. of Biol. Chem., 263(17): 8480-8484 (1988).
Hoffman, E. P., et al., N.E. J. Med., 318(21): 1363-1368 (1988).
Zubrzycka-Gaarn, E. E., et al., Nature, 333: 466-469 (1988).
Arahata, K., et al., Nature, 333: 861-863 (1988).
Bonilla, E., et al., Cell, 54: 447-452 (1988).
Cooper, B. J., et al., Nature, 334: 154-156 (1988).
Campbell, K. P., and Kahl, S. D., Nature, 338: 259-262 (1989).
Ervasti, J. M. et al., Nature, 345: 315-319 (1990).
A. O. Jorgensen et al., The Journal of Cell Biology 110: 1173-1185 (1990).
Campbell Kevin P.
Ervasti James M.
Gaver Mitchell G.
Kahl Steven D.
Ohlendieck Kay
Kepplinger Esther L.
University of Iowa Research Foundation
Wortman Donna
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