Radiant energy – Ionic separation or analysis – Methods
Reexamination Certificate
2006-09-19
2006-09-19
Wells, Nikita (Department: 2881)
Radiant energy
Ionic separation or analysis
Methods
C250S281000, C250S292000
Reexamination Certificate
active
07109474
ABSTRACT:
Method and apparatus, including computer program products, implement techniques for operating a mass spectrometer that includes a source of ions, a mass analyzer, and a detector, in which a gain of the detector or the number of ions detected by the detector is calculated based on intensity measurements for ions having a plurality of different m/z values. In particular implementations, the detector gain or the number of ions detected by the detector can be calculated based on a ratio of or difference between intensity values for at least two of the ions having different m/z values.
REFERENCES:
patent: 4746794 (1988-05-01), French et al.
patent: 5157260 (1992-10-01), Mylchreest et al.
patent: 5420925 (1995-05-01), Michaels
patent: 5463219 (1995-10-01), Buckley et al.
patent: 6265714 (2001-07-01), Shimomura
patent: 6674068 (2004-01-01), Kammei
Parminder Kaur et al., “Use Of Statistical Methods For Estimation Of Total Number Of Charges In A Mass Spectrometry Experiment”, Analytical Chemistry, 2004, pp. A-G.
Michael J. Kristo and Christie G. Ente, “System For Simultaneous Count/Current Measurement With A Dual-Mode Photon/Particle Detector”, Rev. Scientific Instruments vol. 59, No. 3, Mar. 1988, pp. 438-442.
William J. Fies, “A Method For Measuring The Gain Of An Electron Multiplier”, International Journal Of Mass Spectrometry and Ion Processes, vol. 82, Jul. 1987, pp. 111-127.
Keith Birkinshaw, “Special Feature: Tutorial, Fundamentals Of Focal Plane Detectors”, Journal of Mass Spectrometry, vol. 32, 1997, pp. 795-806.
G. Lakits et al., “Electron Emission From Metal Surfaces Bombarded By Slow Neutral And Ionized Particles”, Nuclear Instruments and Methods In Physics Research B48, 1990, pp. 597-603.
G. Laktis et al.., “Statistics Of Ion-Induced Electron Emission From A Clean Metal Surface”, Rev. Scientific Instruments, vol. 60, No. 10, Oct. 1989, pp. 3151-3159.
Fish & Richardson P.C.
Johnston Phillip A.
Thermo Finnigan LLC
Upham Sharon
Wells Nikita
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