Electricity: measuring and testing – Determining nonelectric properties by measuring electric... – Semiconductors for nonelectrical property
Patent
1992-11-24
1994-05-03
Wieder, Kenneth A.
Electricity: measuring and testing
Determining nonelectric properties by measuring electric...
Semiconductors for nonelectrical property
324158T, 324705, 204403, 204418, G01N 2700
Patent
active
053090853
ABSTRACT:
A measuring circuit with a biosensor utilizing ion sensitive field effect transistors having a simplified structure and is advantageous to integration. The measuring circuit comprises two ion sensitive FET input devices composed of an enzyme FET having an enzyme sensitive membrane on the gate and a reference FET, and a differential amplifier for amplifying the outputs of the enzyme FET and the reference FET. The drift phenomena of the ISFETs due to the use of a non-stable quasi-reference electrode as well as the temperature dependence thereof can be eliminated by the differential amplifier consisting of MOSFETs having the same channel as the ISFETs. The ISFET biosensor and the measuring circuit can be integrated into one chip.
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Brown Glenn W.
Bushnell Robert E.
Wieder Kenneth A.
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