Measuring cellular metabolism of immobilized cells

Details Measuring cellular metabolism of immobilized cells Measuring cellular metabolism of immobilized cells

2006-11-28

2006-11-28

Forman, B J (Department: 1634)

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving nucleic acid

C435S174000, C435S283100, C422S068100, C428S410000

Reexamination Certificate

active

07141369

ABSTRACT:
This invention uses a receptor molecule such as an antibody etc immobilized to a chip for a solid phase, and a sensor such as a pH electrode or an oxygen electrode or a glucose electrode for a search device. After immobilizing specific living cells by a bio-specific recognition reaction (a special immunity bond reaction) and washing the solid phase chip, one can measure the change of pH or oxygen consumption or glucose consumption from the metabolism of the specific living cells in substrate solution. This makes it possible to measure the activity and quantity of living cells specifically, accurately and quickly.

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