Surgery – Truss – Pad
Patent
1995-01-26
1998-02-03
Jastrzab, Jeffrey R.
Surgery
Truss
Pad
A61B 50452
Patent
active
057133670
ABSTRACT:
The alternans pattern of cycle-to-cycle variability in physiologic waveforms is assessed by applying transducers to a subject, recording physiologic signals, and analyzing the alternans pattern of variation in waveform morphology. Preferred embodiments include methods and apparatus for measuring and assessing alternans in the presence of physiologic stress, such as exercise, in order to induce or increase the amplitude of the alternans, improvements in signal processing to improve the sensitivity and specificity of the analysis, improvements to provide real-time analysis and feedback to the operator conducting the recording of physiologic signals, reduction in the effect of intercycle interval variability on waveform variability, reduction in the effects of respiration on the alternans measurement, improved means for determining the statistical significance of the alternans measurement, handling of abnormal beats such as atrial and ventricular premature beats, choosing of data epochs over which to perform the alternans measurement, using multiple electrodes to improve the accuracy of the alternans measurement, and combining measurement of alternans with other cardiovascular diagnostic tests to facilitate and improve the combined diagnostic capability.
REFERENCES:
patent: 3868947 (1975-03-01), Holsinger
patent: 4038536 (1977-07-01), Feintuch
patent: 4082087 (1978-04-01), Howson
patent: 4362165 (1982-12-01), Carmon et al.
patent: 4422459 (1983-12-01), Simson
patent: 4448199 (1984-05-01), Schmid
patent: 4458691 (1984-07-01), Netravali
patent: 4458692 (1984-07-01), Simson
patent: 4492235 (1985-01-01), Sitrick
patent: 4583549 (1986-04-01), Manoli
patent: 4630204 (1986-12-01), Mortara
patent: 4732157 (1988-03-01), Kaplan et al.
patent: 4751931 (1988-06-01), Briller et al.
patent: 4763660 (1988-08-01), Kroll et al.
patent: 4781201 (1988-11-01), Wright et al.
patent: 4793361 (1988-12-01), DeFault
patent: 4802222 (1989-01-01), Weaver
patent: 4802491 (1989-02-01), Cohen et al.
patent: 4955381 (1990-09-01), Way et al.
patent: 4979110 (1990-12-01), Albrecht et al.
patent: 4991587 (1991-02-01), Blakeley et al.
patent: 5010888 (1991-04-01), Jadvar et al.
patent: 5117828 (1992-06-01), Metzger et al.
patent: 5148812 (1992-09-01), Verrier et al.
patent: 5188116 (1993-02-01), Pommrehn et al.
patent: 5234404 (1993-08-01), Tuttle et al.
patent: 5237995 (1993-08-01), Cano
patent: 5259387 (1993-11-01), dePinto
patent: 5265617 (1993-11-01), Verrier et al.
patent: 5305446 (1994-04-01), Leach et al.
patent: 5318037 (1994-06-01), Evans et al.
patent: 5323783 (1994-06-01), Henkin et al.
patent: 5341811 (1994-08-01), Cano
patent: 5348020 (1994-09-01), Hutson
patent: 5437285 (1995-08-01), Verrier et al.
patent: 5560370 (1996-10-01), Verrier et al.
patent: 5570696 (1996-11-01), Arnold et al.
Adam et al., "Estimation of Ventricular Vulnerability to Fibrillation Through T-Wave Time Series Analysis", Computers in Cardiology, pp. 307-310 (1981).
Adam et al., "Ventricular Fibrillation and Fluctuations in the Magnitude of the Repolarization Vector", Computers in Cardiology, pp. 241-244 (1982).
Adam et al., "Fluctuations in T-Wave Morphology and Susceptibility to Ventricular Fibrillation", J. Electrocardiology 17:209-218 (1984).
Mortara, "Source Consistency Filtering --A New Tool for ECG Noise Reduction", IEEE, pp. 125-128 (1992).
Nearing et al., "Dynamic Tracking of Cardiac Vulnerability by Complex Demodulation of the T Wave", Science 252:437-252 (1991).
Nearing et al., "Personal Computer System for Tracking Cardiac Vulnerability by Complex Demodulation of the T Wave", J. Appl. Physiol. 74:2606-2612 (1993).
Pedretti et al., "Prediction of Late Arrhythmic Events After Acute Myocardial Infarction . . . Sustained Monomorphic Ventricular Tachycardia", Am. J. Cardiol. 71:1131-1141 (1993).
Ring et al., "Exercise-Induced ST Segment Alternans", American Heart Journal 111:1009-1011 (1986).
Ritzenberg et al., "Period Multupling-Evidence for Nonlinear Behavior of the Canine Heart", Nature 307:159-161 (1984).
Rosenbaum et al., "Electrical Alternans and Vulnerability to Ventricular Arrhythmias", New Engl. J. of Medicine 330:235-241 (1994).
Shvartsman et al., "Multichannel Signal Processing Based on Logic Averaging", IEEE Transactions on Biomedical Engineering 7:531-536 (1982).
Smith et al., "Subtle Alternating Electrocardiographic Morphology as an Indicator of Decreased Cardiac Electrical Stability", Computers in Cardiology, pp. 109-112 (1985).
Smith et al., "Electrical Alternans and Cardiac Electrical Instability", Circulation 77:110-121 (1988).
Smith, "The Stochastic Nature of Cardiac Electrical Instability: Theory and Experiment", thesis (1985).
Verrier et al., "Electrophysiologic Basis for T Wave Alternans as an Index of Vulnerability to Ventricular Fibrillation", Cardiovasc. Electrophysiol. 5:445-461 (1994).
Flowers et al., "Surface Recording of His-Purkinje Activity on an Every-beat Basis Without Digital Averaging" Circulation 63, No. 4, Apr., 1981, Division of Cardiology, University of Louisville, pp. 948-952.
Flowers et al., "Analysis of PR Subintervals in Normal Subjects and Early Studies in Patients With Abnormalities of the Conduction System Using Surface His Bundle Recordings", JACC vol. 2, No. 5, Nov. 1983:939-46.
Zimmermann et al., "Beat-tobeat detection of ventricular late potentials with high-resolution electrocardiography", American Heart Journal, Progress in Cardiology, vol. 121, No. 2, part 1, pp. 576-585.
El-Sherif et al., "Beat-to-Beat High-Resolution Electrocardiogram: Technical and Clinical Aspects", Progress in Cardiovascular Diseases, vol. XXXv, No. 6 (May/Jun.) 1993: pp. 407-415.
El-Sharif et al., "Appraisal of a Low Noise Electrocardiogram", J. Am. Coll. Cardiol. 1983:1(2):456-67.
Mortara, "Source Consistency Filtering-Application to Resting ECGs", Journal of Electrocardiol., vol. 25 Supplement, pp. 200-206, 1992.
Mortara, "Source Consistency Filtering --A New Tool for ECG Noise Reduction", In Computers in Cardiology, IEEE, pp. 125-128, Piscataway, NJ, 1991.
Cano et al., "Enhancement of Low-Level ECG Components in Noise with Time-sequenced Adaptive Filtering", Journal of Electrocardiology, vol. 23 Supplement, pp. 176-183, 1990.
Meyer et al., "Electrocardiogram Baseline Noise Extimation and Removal Using Cubic Splines and State-Space Computation Techniques", Computers and Biomedical Research 10, 459-470 (1977).
Evans et al., "Redundancy Reduction for Improved Display and Analysis of Body Surface Potential Maps", Circulation Research, vol. 49, No. 1, pp. 197-203, Jul. 1981.
Uijen et al., "The Number of Signals in Multilead ECGs in Individuals", Journal of Electrocardiology, vol. 26, No. 2, pp. 107-116, 1993.
Damen et al., "The Use of the Singular Value Decomposition in Electrocardiology", Medical & Biological Engineering & Computing, pp. 473-482, Jul., 1982.
Salerno et al., "Ventricular arrhythmias during acute myocardial ischaemia in man . . . ", European Heart Journal (1986) 7 (Supplement A), pp. 63-75.
Zareba et al., "T Wave Alternans," J Am Coll Cardiol (1994), vol. 23, pp. 1541-1546.
Albrecht Paul
Arnold Jeffrey M.
Cohen Richard J.
Librett Kevin S.
Cambridge Heart, Inc.
Jastrzab Jeffrey R.
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