Measurement of the activated partial thromboplastin time (APTT)

Chemistry: analytical and immunological testing – Clotting or clotting factor level tests

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436 34, 435 13, 514 2, 530383, G01N 2117

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active

055061460

ABSTRACT:
A method for the determination of the activated partial thromboplastin time (APTT) in a one-step reaction, in which the determination of APTT is initiated by contacting a reagent that contains the substances necessary for the APTT determination in a premixed form, with the sample to be tested. A reagent which contains the substances necessary for the APTT determination is also disclosed.

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Oberhardt et al., Clin. Chem., "Dry Reagent Thechnology for Rapid, Convenient Measurements of Blood Coagulation and Fibrinolysis", 37/4, 520-526 (1991).
Ponjee et al., Clin. Chem., "One-Step Chromogenic Equivalent of Activated Partial Thromboplastin Time Evaluated for Clinical Application", 37/7, 1235-1244 (1991).
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International Publication No. WO 90/11368, published Oct. 4, 1990.

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