Measurement of liquid phase gastric emptying

Details Measurement of liquid phase gastric emptying Measurement of liquid phase gastric emptying

1996-09-05

1998-07-28

Kight, John

Drug, bio-affecting and body treating compositions

Radionuclide or intended radionuclide containing; adjuvant...

In an organic compound

424 111, 424 117, 424 165, 424439, 435 4, 435 29, A61K 5100, A61M 3614

Patent

active

057859493

ABSTRACT:
A drink adapted to be consumed by a patient to enable measurement of gastric emptying of the liquid phase, is a fruit juice having mixed and suspended therein a quantity of Spirulina platensis alga grown in a .sup.13 CO.sub.2 atmosphere. These single cell organisms pass from the stomach into the small intestine where they are digested, absorbed and oxidized to produce a detectible rise in the level of .sup.13 CO.sub.2 in the patient's breath which is sampled and the measured valves plotted to enable determination of gastric emptying rate abnormalities.

REFERENCES:
patent: 5140993 (1992-08-01), Opekun, Jr. et al.
patent: 5233997 (1993-08-01), Klein et al.
Bjorman et al (1989), vol. 96, No. 5, Part 2, p. A46, "Comparison of the 13C Bicarbonate Breath Test with radiolabeled Meals in Gastric Emptying." (Gastroenterology).
Klein et al (1987), vol. 92, No. 5, Part 2, p. 1470, "The 13C-Bicarbonate Meal Breath Test: A New Noninvasive Measurement of Gastric Emptying of Liquid or Solid Meals". (Gastroenterology).
Maes et al, (1996), Gut, vol. 38, pp. 23-27, "Relation between gastric emptying rate and rate of intraluminal lipolysis".
Maes et al (1994), Journal of Nuclear Medicine, vol. 35, No. 5, pp. 824-831, "Combined Carbon-13 Glycine/Carbon-14-Octanoic Acid Breath Test to Monitor Gastric Emptying Rates of Liquids and Solids".
Maes et al (1995), Gut, vol. 36, pp. 183-188, "Relation between gastric emptying rate and energy intake in children compared with adults". Emptying of Liquids in Both Liquid and Semisolid Test Meals", by Barbara Braden, Stefan Adams, Li-Ping Duan, Karl-Heinz Orth, Frank-Dieter Maul, Bernhard Lembcke, Gustav Hor and Wolfgang F. Caspary, Gastroenterology, vol. 108, No. 4, pub. Apr., 1995, pp. 1048-1055 (8 pages).

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