Measurement of body compounds

Details Measurement of body compounds Measurement of body compounds

2008-03-11

2008-03-11

Winakur, Eric (Department: 3768)

Surgery

Diagnostic testing

Measuring or detecting nonradioactive constituent of body...

C600S309000

Reexamination Certificate

active

10465490

ABSTRACT:
The present invention provides a method for identifying a concentration of a compound within a part of a subject. The method involves measuring the amount of electromagnetic radiation reflected by, or transmitted through the part with a detector, and using a quantitative mathematical analysis to determine the concentration of the compound in one, or more than one compartment, including a blood, interstitial, cellular, lymph, or bone compartment, of the part. A corrected concentration of the compound may be then determined within a compartment of interest, or a total concentration of the compound may be accurately determined. Preferably, the compound is glucose. From this determination, a clinical condition in a human or animal may be made by correlating the concentration of a measured compound in the compartment of a part of the human or animal to a clinical condition in need of treatment.

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Tierney et al., 2000, “Electroanalysis of Glucose in Transcutaneously Extracted Samples”, Electroanalysis 12:666-71.

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