Measurement cell and method for the analysis of liquids

Details Measurement cell and method for the analysis of liquids Measurement cell and method for the analysis of liquids

2008-06-24

2008-06-24

Williams, Hezron E. (Department: 2856)

Measuring and testing

Liquid analysis or analysis of the suspension of solids in a...

Content or effect of a constituent of a liquid mixture

C356S501000

Reexamination Certificate

active

07389679

ABSTRACT:
This invention relates to a liquid measurement cell for micromechanical sensors, so-called cantilever sensors. These sensors are e.g. used for the detection of biomolecules without the need for fluorescent or radioactive labelling. These measurements are usually carried out in liquids, where air or gas bubbles present in the analyte inside the measurement cell can significantly affect measurement results or even destroy the sensor. In a measurement cell according to this invention, a closed gas volume is present above the liquid level. Consequently, gas or air bubble can be constantly absorbed by the gas volume and do not come in contact with the cantilever sensors. The measurement cell is further characterised by a very low volume in the order of microliters and can be combined with various optical or piezoelectrical/piezoresistive read-out methods.

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Godin, Michel. “Combined In Situ Micromechanical Cantilever-Based Sensing and Ellipsometry”. Review of Scientific Instruments, vol. 74, No. 11 (Nov. 2003): 4902-4907.

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