Chemical apparatus and process disinfecting – deodorizing – preser – Analyzer – structured indicator – or manipulative laboratory... – Means for analyzing liquid or solid sample
Patent
1996-05-13
1998-11-17
Soderquist, Arlen
Chemical apparatus and process disinfecting, deodorizing, preser
Analyzer, structured indicator, or manipulative laboratory...
Means for analyzing liquid or solid sample
128635, 204403, 204416, 422 61, 422 8201, 422 8202, 422 8203, 422 8204, 422 8205, 436 66, 436 68, 436 74, 436 79, 436 93, 436 96, 436108, 436110, 436113, 436150, 436163, G01N 2700, G01N 2100, G01N 3300
Patent
active
058371990
DESCRIPTION:
BRIEF SUMMARY
CROSS-REFERENCE TO RELATED APPLICATION
The present invention claims priority under 35 U.S.C..sctn.119 of German Patent Application No. P 44 27 725.3.
BACKGROUND OF THE INVENTION
1. Field of the Invention
The invention relates to a measurement apparatus comprising a container in the form of a syringe into which a fluid can be taken up through at least one cannula as an intake device, a sensor being integrated in or on the wall of the container in such a way that it can come into contact with the fluid taken up into the cavity of the container. The invention further relates to the use of such a measurement apparatus.
2. Discussion of Background Information
In order to determine the concentrations in a solution of dissolved ions or molecules by means of chemical sensors, the solution to be investigated is removed from its point of origin, filled into an appropriate vessel, and measurement is undertaken by submerging the sensor.
Another measurement method operates according to the throughflow principle. In this case the solution for analysis flows past a sensor. For this purpose also the solution to be analysed is firstly removed and then passed over the sensor. A measurement principle of this type is described for example in J. Ruzicka, E. H. Hansen: Flow Injection-Analysis, New York, John Wiley Sous, 1981. Both these methods are only of restricted usefulness for on-site analysis, which is gaining importance in modern analysis, as they are too complex, and require qualified personnel. Analysis platelets or test strips were developed for these particular applications.
Analysis platelets are used by various commercially-available systems, especially for blood-testing (e.g. Kodak Ektachem DT II system, Kodak AG, Klinische Chemie, Postfach 60 03 45, Stuttgart). In this case blood is firstly removed, and the blood is applied by means of a pipette. Measurement is then undertaken.
A similar procedure takes place in measurement with electrochemical test strips.
Thus, for rapid on-site analysis, the sample is removed from its point of origin and applied to the sensor in a second step.
This method of operation is however disadvantageous for various analyses, particularly blood analyses, analysis of toxic and sensitive substances.
In the analysis of infectious analytical media, e.g. blood, it is possible, due to incautious operation with drops of blood, that infection may occur, or spillage of the sample. A further disadvantage is that an alteration in the concentration of the analytical subject is possible in an open drop of blood by evaporation or absorption of air components (e.g. alteration in the pH value). Finally, it is desirable in many cases to carry out a calibration before the actual measurement, principally because the one-time sensors used in the procedures described above cannot always be manufactured in a reproducible manner. Such calibration, however, is not possible with the methods described above.
The i-STAT sensor system (i-STAT Corporation 303A College Road East, Princeton) was developed as a solution to this problem. Here one-time sensors are located in a cartridge in a flow duct. A calibrating solution is located in a plastics bag in the cartridge. Calibration and measurement are effected in accordance with a complex measurement procedure. firstly the sample is filled into the forward region of the flow duct by capillary action. Then the plastics bag is destroyed by pressure of a spike on the cartridge. The calibrating solution flows over the sensor. Next the sample is passed over the sensor by pressure on the cartridge. This measuring system permits rapid on-site analysis of concentrations, but is expensive because of its complex structure. Moreover, the cartridge is not directly suitable for sampling.
SUMMARY OF THE INVENTION
Proceeding from this point, the object of the present invention is to propose a measurement apparatus by means of which it is possible to undertake a simple, cost-effective and reproducible on-site analysis. At the same time, precise measurement results are to be obt
REFERENCES:
patent: 4318884 (1982-03-01), Suzuki
patent: 4339317 (1982-07-01), Meiattini et al.
patent: 4899759 (1990-02-01), Pederson et al.
patent: 5046496 (1991-09-01), Betts et al.
patent: 5114859 (1992-05-01), Kagenow
patent: 5145565 (1992-09-01), Kater et al.
patent: 5208147 (1993-05-01), Kagenow et al.
patent: 5449494 (1995-09-01), Seeney
V. A. Knight J. Appl. Physiol. 1976, 40, 441-442.
Institut Fur Chemo-Und Biosensorik Munster E.V.
Soderquist Arlen
LandOfFree
Measurement apparatus for analyzing fluids does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Measurement apparatus for analyzing fluids, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Measurement apparatus for analyzing fluids will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-881093