Measles virus recombinant poxvirus vaccine

Details Measles virus recombinant poxvirus vaccine Measles virus recombinant poxvirus vaccine

1993-06-08

1996-04-02

Mosher, Mary E.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Recombinant virus encoding one or more heterologous proteins...

4242121, 4242131, 4242321, 4352351, 4353201, A61K 39165, A61K 39175, A61K 39285, C12N 701

Patent

active

055038344

ABSTRACT:
What is described is a recombinant poxvirus, such as vaccinia virus or canarypox virus, containing foreign DNA from Morbillivirus. In one embodiment, the foreign DNA is expressed in a host by the production of a measles virus glycoprotein. In another embodiment, the foreign DNA is expressed in a host by the production of at least two measles virus glycoproteins. What is also described is a vaccine containing the recombinant poxvirus for inducing an immunological response in a host animal inoculated with the vaccine. By the present invention, cross-protection of dogs against canine distemper is obtained by inoculating the dog with the recombinant poxvirus.

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