Means to promote the neutralization reaction between particulate

Details Means to promote the neutralization reaction between particulate Means to promote the neutralization reaction between particulate

1987-04-17

1989-12-26

Doll, John

Drug, bio-affecting and body treating compositions

Inorganic active ingredient containing

Elemental fluorine or fluorine compound

210753, 423308, 423309, 423431, 423490, 424687, A01N 5910

Patent

active

048897256

ABSTRACT:
A means for promoting the neutralization reaction between particulate calcium carbonate and ionized phosphate by adding a material formed by the reaction of particulate calcium carbonate and dilute hydrofluoric acid. The products of this invention are useful in lowering serum phosphate levels in patients undergoing renal dialysis, and are also useful as antacids. These products are also useful in the treatment of water and waste water to lower phosphate content.

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P. Moriniere et al., Comparison of 1.alpha.-OH-Vitamin D.sub.3 and High Doses of Calcium Carbonate for the Control of Hyperparathyroidism and Hyperaluminemia in Patients on Maintenance Dialysis, Nephron, 39:309-315, (1985).
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E. Slatopolsky et al., Calcium Carbonate as a Phosphate Binder in Patient With Chronic Renal Failure Undergoing Dialysis, New England J. Med., vol. 315, No. 3, (1986).

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