Means for sequential solid phase organic synthesis and methods u

Details Means for sequential solid phase organic synthesis and methods u Means for sequential solid phase organic synthesis and methods u

1985-03-25

1986-12-23

Kittle, John E.

Stock material or miscellaneous articles

Hollow or container type article

Cellular material derived from plant or animal source

139389, 383102, 525 5411, D03D 104, B65D 3301, C08F28300

Patent

active

046312110

ABSTRACT:
A means for carrying out sequential, solid phase syntheses is disclosed as are methods of its use. The synthesis means comprises a foraminous container that encloses reactive particles. The particles are larger than any of the foraminae and have a known amount of covalently linked organic synthesis reactive functionality that is capable of reacting during the organic syntheses. The container and particles are substantially insoluble in water.

REFERENCES:
patent: 3544404 (1970-12-01), Johnson et al.
patent: 4226857 (1980-11-01), Momany
patent: 4282143 (1981-08-01), Sarantakis
patent: 4304692 (1981-12-01), Hughes et al.
patent: 4483964 (1984-11-01), Urdea et al.
patent: 4507433 (1985-03-01), Miller et al.
Merrifield, Solid Phase Peptide Synthesis, Journal American Chemical Society, vol. 85, pp. 2149-2154, 1963.

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