Means for monitoring the status of control of ketoacidosis-prone

Chemistry: analytical and immunological testing – Rate of reaction determination

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422 56, 436 95, 436128, 436130, 436131, G01N 3352, G01N 3364, G01N 3366

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043979564

ABSTRACT:
Method and test system for monitoring the status of control of ketoacidosis-prone diabetics using pseudo-kinetic methods. Pseudo-kinetic clinical information is obtained by analysis of a single blood sample in which the blood glucose level is determined along with one or more additional indicator analytes present in patient blood, serum or plasma. The additional indicator analyte(s) provide a "historical" picture of recent events within the patient relating to glucose metabolism which, when analyzed in conjunction with the blood glucose level, provides, from a single sample, a holistic view of the degree of metabollic control in the diabetic patient which is otherwise obtainable at the present time only by the much less desirable process of drawing and analyzing multiple samples over a period of time. The additional indicator analyte may be ketone bodies.

REFERENCES:
patent: 3915644 (1975-10-01), Walraven
patent: 3954412 (1976-05-01), Ogawa
patent: 4147514 (1979-04-01), Magers
patent: 4160646 (1979-07-01), Furutani
patent: 4336330 (1982-06-01), Bauer
Chemical Abstracts, 95: 22453p (1981).

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