Liquid purification or separation – Processes – Including controlling process in response to a sensed condition
Patent
1996-07-25
1998-11-03
Drodge, Joseph W.
Liquid purification or separation
Processes
Including controlling process in response to a sensed condition
7386107, 7386118, 12866001, 128668, 210646, 210929, 604 4, B01D 1712, B01D 6132, G01F 500
Patent
active
058303650
ABSTRACT:
The invention relates to a means for determining hemodynamic parameters, such as cardiopulmonary recirculation, fistula flow and cardiac minute output during an extracorporeal blood treatment, in which blood is conducted to a dialyzer (3) by way of arterial branch (8, 8') of extracorporeal path (2) which is fluidly connected to a segment (9, 12) of a fistula (10), then returned by way of venous branch (11, 11') of the extracorporeal path which is fluidly connected to the other segment (12, 9) of the fistula. The hemodynamic parameters are determined by two recirculation fraction measurements taken in quick succession and which are performed automatically by the apparatus before and after the blood flow is reversed. In a computer-memory unit (22) cardiopulmonary recirculation is calculated based on the recirculation fraction during normal blood flow together with the recirculation fraction during reversed blood flow. To determine the recirculation fraction the concentration of an indicator solution is altered in venous branch (11, 11') of the extracorporeal path and the change in concentration of indicator solution resulting from recirculation in arterial branch (8, 8') of extracorporeal path (2) is recorded. In a preferred embodiment of the present invention indicator solution in the form of a predetermined amount of dialyzate is infused into the extracorporeal path by back filtration.
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Allen Kenneth R.
Drodge Joseph W.
Fresenius AG
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