Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Preparing compound containing saccharide radical
Reexamination Certificate
2006-11-14
2006-11-14
Yu, Misook (Department: 1642)
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Preparing compound containing saccharide radical
C435S007230, C435S006120, C436S518000, C436S501000
Reexamination Certificate
active
07135311
ABSTRACT:
The invention relates to a method for detecting carcinomas in a biological sample, comprising identifying FGFR3 mutations.
REFERENCES:
Karoui et al., (2001, Oncogene, vol. 20, pp. 5059-5061).
Chesi, M et al; “Frequent Translocation t(4;14)(p16.3;q32.3) in Multiple Myeloma is Associated with Increased Exxpression and Activating Mutations of Fibroblast Growth Factor Receptor 3”; Nature Genetics, vol. 15, No. 3; 1997; pp. 260-264; XP001030990.
Webster, M. K. et al; “Enhanced Signaling and Morphological Transformation by a Membrane-Localized Derivative of the Fibroblast Growth Factor Receptor 3 Kinase Domain”; Mol. Cell Biol.; vol. 17, No. 10; 1997; pp. 5739-5747; XP002181674.
Li, Z.H. et al; “An Activating Mutation of the Myeloma Associated Ontogene Fibroblast Growth Factor Receptor 3 (FGFR3) has Hematopoietic Transforming Potential in Mice”; Blood; vol. 92, No. 10; Suppl. 1 (Part 1 of 2); Nov. 15, 1998; p. 383A; XP001030987.
Plowright, E.E. et al; “An Activating Mutation of the Myeloma Associated Oncogene Fibroblast Growth Factor Receptor 3 (FGFR3) Promotes Interleukin-6 (IL-6) Independence and Upregulation of bcl-xL”; Blood; vol. 92, No. 10, Suppl 1 (Part 1 of 2); Nov. 15, 1998; p. 383A; XP002181675.
Cappellen, D. et al; “Frequent Activating Mutations of FGFR3 in Human Bladder and Cervix Carcinomas” Nature Genetics; vol. 23; Sep. 1999; pp. 18-20; XP002181676.
David Cappellen
David Ricol
Dominique Chopin
Francois Radvanyi
Jean-Paul Thiery
Centre National de la Recherche Scientifique "CNRS"
Institut Curie
Nixon & Vanderhye P.C.
Yu Misook
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