Chemistry: molecular biology and microbiology – Process of mutation – cell fusion – or genetic modification – Introduction of a polynucleotide molecule into or...
Reexamination Certificate
2011-06-21
2011-06-21
Belyavskyi, Michail A (Department: 1644)
Chemistry: molecular biology and microbiology
Process of mutation, cell fusion, or genetic modification
Introduction of a polynucleotide molecule into or...
C435S326000, C435S372000
Reexamination Certificate
active
07964406
ABSTRACT:
The invention provides a method for producing a stabilized cell of interest, said method comprising providing a stem cell and/or a precursor cell of said cell of interest with a nucleic acid sequence which, when present in said cell of interest, is capable of stabilizing said cell of interest, providing a non-human animal with said stem cell and/or precursor cell, allowing generation of said cell of interest in said animal, and obtaining said cell of interest. Said animal is preferably provided with a human stem cell and/or human precursor cell, allowing production of a human cell line.
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Berkhout Benjamin
Markusic David M.
Seppen Jurgen E.
Spits Hergen
Weijer Kees
Academisch Medisch Centrum Bij De Universiteit Van Amsterdam
Belyavskyi Michail A
TraskBritt P.C.
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