Mdm2 splice variants

Details Mdm2 splice variants Mdm2 splice variants

2007-09-25

2007-09-25

Foley, Shanon (Department: 1642)

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

Reexamination Certificate

active

10980519

ABSTRACT:
The invention provides polypeptide and polynucleotide splice variants of the mouse Mdm2 gene, including Mdm2-b, which is homologous to the human Hdm2-b variant, as well as host cells, vectors and transgenic mice comprising the variants, and methods for the use thereof.

REFERENCES:
patent: 5912143 (1999-06-01), Bandman et al.
Bowie et al (Science, 1990, 257:1306-1310).
Burgess et al (J of Cell Bio. 111:2129-2138, 1990).
Lazar et al (Molecular and Cellular Biology, 1988, 8:1247-1252).
Chen et al. (1996, Mol. and Cell. Biol. 16(5):2445-2452).
GenBank Accession No. NM 002392 (as downloaded Jun. 5, 2006).
Boehringer Mannheim Biochemicals, 1994 Catalog, p. 93.

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