MCH4 and MCH5, apoptotic protease, nucleic acids encoding and me

Details MCH4 and MCH5, apoptotic protease, nucleic acids encoding and me MCH4 and MCH5, apoptotic protease, nucleic acids encoding and me

1996-06-14

1998-07-28

Sisson, Bradley L.

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Recombinant dna technique included in method of making a...

435 701, 4351723, 435183, 435219, 4352523, 4353201, 530324, 530350, 536 231, 536 235, 536 2431, 935 1, 935 22, 935 33, 935 66, C12P 2106, A61K 3800, C07H 2104, C12N 1500

Patent

active

057861730

ABSTRACT:
The invention provides an isolated gene encoding Mch4 or an isolated gene encoding Mch5 as well as functional fragments thereof. Also provided are isolated nucleic acid sequences encoding Mch4 or Mch5 or functional fragment thereof. The gene or nucleic acid sequences can be single or double stranded nucleic acids corresponding to coding or non-coding strands of the Mch4 or Mch5 nucleotide sequences. Also provided are genes and nucleic acids encoding functional fragments such as the FADD-like domains Mch4A, Mch4B, Mch5A and Mch5B. Isolated Mch4 or Mch5 polypeptides or functional fragments thereof including the FADD-like domains Mch4A, Mch4B, Mch5A and Mch5B are also provided.

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