MCH antagonists for the treatment of obesity

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

Reexamination Certificate

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Details

C544S364000

Reexamination Certificate

active

07345042

ABSTRACT:
The present invention discloses methods of using antagonists for melanin-concentrating hormone (MCH), to treat obesity, metabolic disorders, eating disorders such as hyperphagia, and diabetes, as well as novel compounds which are antagonists for melanin-concentrating hormone (MCH). In other aspects, the invention is directed to pharmaceutical compositions comprising such MCH antagonists as well as methods for preparing such compounds. Compounds of the invention generally have the structure:where the substituents are as defined herein.

REFERENCES:
patent: 6391865 (2002-05-01), Baroudy et al.
Vippagunta et al. Advanced Drug Delivery Reviews, vol. 48, p. 3-26 (2001).

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