MCH antagonists for the treatment of obesity

Details MCH antagonists for the treatment of obesity MCH antagonists for the treatment of obesity

2006-05-16

2006-05-16

Wilson, James O. (Department: 1623)

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

C546S001000, C514S277000, C514S359000

Reexamination Certificate

active

07045636

ABSTRACT:
The present invention discloses compounds, which are novel antagonists for melanin-concentrating hormone (MCH), as well as methods for preparing such compounds. In another embodiment, the invention discloses pharmaceutical compositions comprising such MCH antagonists as well as methods of using them to treat obesity, metabolic disorders, eating disorders such as hyperphagia, and diabetes.

REFERENCES:
patent: 5908830 (1999-06-01), Smith et al.
patent: 6245746 (2001-06-01), Chamberland et al.
patent: 1219294 (2001-03-01), None
patent: WO 02/057233 (2002-07-01), None
patent: WO 02/083134 (2002-10-01), None
Shimada et al., Mice Lacking Melanin Concentrating Hormone are Hypophagic and Lean,Nature, vol. 396 (Dec. 17, 1998), pp. 670-673.
International Search Report PCT/US 02/33869 for CV01510K—6 Pages.

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