MCH antagonists and their use in the treatment of obesity

Details MCH antagonists and their use in the treatment of obesity MCH antagonists and their use in the treatment of obesity

2005-05-31

2005-05-31

Wilson, James O. (Department: 1623)

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

C546S223000, C546S248000

Reexamination Certificate

active

06900329

ABSTRACT:
The present invention discloses compounds which, are novel antagonists for melanin-concentrating hormone (MCH), as well as methods for preparing such compounds. In another embodiment, the invention discloses pharmaceutical compositions comprising such MCH antagonists as well as methods of using them to treat obesity, metabolic disorders, eating disorders such as hyperphagia, and diabetes.

REFERENCES:
patent: 5908830 (1999-06-01), Smith et al.
patent: 6043246 (2000-03-01), Fukami et al.
patent: WO 99/64394 (1999-12-01), None
Shimada et al.,Nature, vol. 396 (Dec. 17, 1998), pp. 670-674.

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