Maytansinoids and use

Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Bacterium or component thereof or substance produced by said...

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2602393P, A61K 31535, C07D49816

Patent

active

042488702

ABSTRACT:
Novel maytansinoids of the formula: ##STR1## wherein R is an alicyclic hydrocarbon group of 3 to 10 carbon atoms, phenyl or heterocyclic group, which may optionally be substituted, and

REFERENCES:
patent: 3896111 (1975-07-01), Kupchan et al.
patent: 4137230 (1979-01-01), Hashimoto et al.
patent: 4162940 (1979-07-01), Higashide et al.
Kupchan et al., "J. Med. Chem.", vol. 21, No. 1, pp. 31-37 (1978).

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