Organic compounds -- part of the class 532-570 series – Organic compounds – Unsubstituted hydrocarbyl chain between the ring and the -c-...
Patent
1995-02-03
2000-01-11
Shah, Mukund J.
Organic compounds -- part of the class 532-570 series
Organic compounds
Unsubstituted hydrocarbyl chain between the ring and the -c-...
C07D24500
Patent
active
060137924
ABSTRACT:
Compounds of formula (I): ##STR1## as single stereoisomers or mixtures thereof and their pharmaceutically acceptable salts inhibit matrix metalloproteases, such as interstitial collagenases, and are useful in the treatment of mammals having disease states alleviated by the inhibition of such matrix metalloproteases, for example arthritic diseases or bone resorption disease, such as osteoporosis.
Castelhano Arlindo Lucas
Horne Stephen
Krantz Alexander
Liak Teng Jiam
Yuan Zhengyu
Kifle Bruck
Shah Mukund J.
Syntex (U.S.A.) Inc.
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