Matrix metalloprotease inhibitors

Details Matrix metalloprotease inhibitors Matrix metalloprotease inhibitors

1990-11-21

1993-02-02

Springer, David B.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

546201, 560312, 562623, C07D40106, C07D20922

Patent

active

051839008

ABSTRACT:
Compounds of the formulas ##STR1## wherein R.sup.1 is H and R.sup.2 is alkyl (3-8C) or wherein R.sup.1 and R.sup.2 taken together are --(CH.sub.2).sub.n -- wherein n=3-5;

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Mullins et al., Biochim. Biophys. Acta (1983) 695:177-214.
Reich et al., Cancer Res. (1988) 48:3307-3312.

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