Synthetic resins or natural rubbers -- part of the class 520 ser – Synthetic resins – From carboxylic acid or derivative thereof
Patent
1995-02-21
1997-01-14
Azpuru, Carlos
Synthetic resins or natural rubbers -- part of the class 520 ser
Synthetic resins
From carboxylic acid or derivative thereof
528354, 528361, 5147723, 5147726, C08G 6306, C08G 6308, C08G 6366, A61K 4732
Patent
active
055940919
ABSTRACT:
The present invention relates to a matrix for sustained-release preparation comprising an ester formed at a terminal carboxyl group of a straight-chain polyester which essentially consists of an .alpha.-hydroxymonocarboxylic acid. The matrix is stable to light, heat, moisture, coloring etc., and is of low toxicity. The sustained-release preparation produced by using the ester of the present invention offers stable drug release over an extended period of time, ensuring sustained stable effect. Furthermore, the sustained-release preparation does not show excess drug release just after administration.
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Igari Yasutaka
Kamei Shigeru
Oka Masahisa
Okamoto Kayoko
Saikawa Akira
Azpuru Carlos
Takeda Chemical Industries Ltd.
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