Matrix for release of active ingredients

Details Matrix for release of active ingredients Matrix for release of active ingredients

1990-03-02

1991-04-16

Page, Thurman

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Matrices

424 78, 424409, 424 763, 424DIG10, 424 84, 523122, A01N 2508, A61L 904, A61L 1546

Patent

active

050081152

ABSTRACT:
A matrix for delivery of active substances such as fragrances and pheromones into the atmosphere is provided which matrix is active substance permeable (including to hydrophilic substances) and is formed of a copolymer which can be softened sufficiently at temperature between 45.degree. C. and 160.degree. C. to incorporate the substances therein without damage caused by heat or chemical reactions, the matrix being formed of a substantially linear block copolymer which is a reaction product of a polydiorganosiloxane which forms soft segments in said reaction product and a diisocyanate which forms hard segments, said copolymer having a glass transition temperature between 45.degree. C. and 160.degree. C. said soft segments comprising from 70 to 99 percent by weight, based on the weight of said copolymer, the average molecular weight of the copolymer being between 15,000 and 500,000.

REFERENCES:
patent: 4136250 (1979-01-01), Mueller
patent: 4235988 (1980-11-01), Fildes et al.
patent: 4554155 (1985-11-01), Allan et al.
patent: 4631329 (1986-12-01), Gornowicz et al.
patent: 4703070 (1987-10-01), Locko
patent: 4793555 (1988-12-01), Lee et al.
patent: 4908208 (1990-03-01), Lee et al.
Yilgor I "Segmented Organosiloxane Copolymers: I. Synthesis of Siloxane--Urea Copolymers", Polymer, vol. 25, pp. 1800-1806.
Tyagi, D. "Segmented Organosiloxane Copolymers: 2. Thermal and Mechanical Properties of Siloxane-Urea Copolymers", Polymer, vol. 25, pp. 1807-1816.

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