Matrix-degrading metalloproteinase

Details Matrix-degrading metalloproteinase Matrix-degrading metalloproteinase

1994-02-22

1996-01-09

Beisner, William H.

Chemistry: molecular biology and microbiology

Enzyme , proenzyme; compositions thereof; process for...

Hydrolase

435188, 435226, 424 941, 424 9467, C12N 950, C12N 996

Patent

active

054828481

ABSTRACT:
An 80 kDa metaloproteinase is found in hormone-dependent human breast cancer cells. The enzyme is active in the presence of calcium, manganese, or magnesium ions. The 80 kDa proteinase is useful for evaluating therapeutic progress and in formulating plans for treatment.

REFERENCES:
Van Den Bruce F., Genes Involved In Tumor Invasion . . . Int J Cancer 52 653-657 1992.

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