Matrix-assisted laser desorption ionization mass...

Chemistry: analytical and immunological testing – Nuclear magnetic resonance – electron spin resonance or other...

Reexamination Certificate

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Reexamination Certificate

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07390672

ABSTRACT:
Provided herein are substrates for matrix-assisted laser-desorption ionization (MALDI) mass spectrometric analysis. Each spot includes 3-hydroxypicolinic acid matrix and no analyte.

REFERENCES:
patent: 5658802 (1997-08-01), Hayes et al.
patent: 5716825 (1998-02-01), Hancock et al.
Nicola et al. “Application of the fast-evaporation sample preparation method for improving quantification of angiotensin II by matrix-assisted laser desorption/ionization”, Parif Communications in Mass Spectrometry, 1995, v. 9, pp. 1164-1171.
Vorm et al. “Improved Resolution and Very High Sensitivity in MALDI TOF of Matrix Surfaces Made by Fast Evaporation”, Analytical Chemistry, 1994, v. 66, pp. 3281-3287.
Znahg et al. “Capillary electrophoresis combined with MALDI-MS spectrometry: continuous deposition on a matrix-precoated membrane tar qet”, J. Mass Spectr., 1996, v. 31. No. 9, pp. 1039-1046.

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