Chemistry: molecular biology and microbiology – Process of mutation – cell fusion – or genetic modification – Introduction of a polynucleotide molecule into or...
Reexamination Certificate
2006-05-30
2006-05-30
Patterson, Jr., Charles L. (Department: 1652)
Chemistry: molecular biology and microbiology
Process of mutation, cell fusion, or genetic modification
Introduction of a polynucleotide molecule into or...
Reexamination Certificate
active
07052913
ABSTRACT:
In one aspect, biocompatible matrices such as sol-gels encapsulating a reaction center may be administered to a subject for conversion of prodrugs into biologically active agents. In certain embodiments, the biocompatible matrices of the present invention are sol-gels. In one embodiment, the enzymeL-amino acid decarboxylase is encapsulated and implanted in the brain to convertL-dopa to dopamine for treatment of Parkinson's disease.
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Eccles
Babich John W.
Bonavia Grant
Zubieta Jon
Ewing James
Foley & Lardner LLP
Molecular Insight Pharmaceuticals, Inc.
Morency Michel
Patterson Jr. Charles L.
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