Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...
Patent
1997-10-03
1999-10-12
Degen, Nancy
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Recombinant dna technique included in method of making a...
4353201, 536 231, 536 241, C12P 2102, C07H 2104, C12N 1563
Patent
active
059653957
ABSTRACT:
The invention provides a human maternally transcribed protein (HMTP) and polynucleotides which identify and encode HMTP. The invention also provides expression vectors, host cells, agonists, antibodies and antagonists. The invention also provides methods for treating disorders associated with expression of HMTP.
REFERENCES:
Oh, B., et al., "Spindlin, a major maternal transcript expressed in the mouse during the transition from oocyte to embryo," Development, 124:493-503 (1997).
Hwang, S., et al., "Genetic mapping and embryonic expression of a novel, maternally transcribed gene Mem3," Mammalian Genome, 7:586-590 (1996).
Rostomily, R., "Expression of Neurogenic Basic Helix-Loop-Helix Genes in Primitive Neuroectodermal Tumors," Cancer Research, 57:3526-3531 (1997).
Gitelman, I., "Twist Protein in Mouse Embryogenesis," Developmental Biology, 189:205-214 (1997).
Hwang, S., et al. (GI 1255172) GenBank Sequence Database (Accession U50734) National Center for Biotechnology Information, National Library of Medicine, Bethesda, Maryland 20894.
Hwang, S., et al. (GI 1255171) GenBank Sequence Database (Accession U50734) National Center for Biotechnology Information, National Library of Medicine, Bethesda, Maryland 20894.
Corley Neil C.
Hillman Jennifer L.
Lal Preeti
Billings, Esq. Lucy J.
Degen Nancy
Incyte Pharmaceuticals Inc.
Muenzen, Esq. Colette C.
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