Maternal multi-nutrient against diabetes-related birth defects

Details Maternal multi-nutrient against diabetes-related birth defects Maternal multi-nutrient against diabetes-related birth defects

2005-12-09

2008-10-21

Padmanabhan, Sreeni (Department: 1617)

Drug, bio-affecting and body treating compositions

Plant material or plant extract of undetermined constitution...

C514S251000

Reexamination Certificate

active

07438933

ABSTRACT:
The present invention provides uses of multi-nutrient supplements to rescue aberrant biochemical pathways and reduce birth defect caused by maternal diabetes. Choice of supplements is based on the ability of each supplement to correct the following hyperglycemia-associated abnormalities: increased reactive oxygen species generation, abnormal membrane phospholipid metabolism, and decreased glutathione synthesis.

REFERENCES:
patent: 6852760 (2005-02-01), Fine et al.
Reece, E. A.; Wu, Y. “Prevention of diabetic embryopathy in offspring of diabetic rats with use of a cocktail of deficient substrates and an antioxidant” Apr. 1997, Am. J. Obstet. Gynecol., vol. 176(4), pp. 790-798/.

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