Materials formable in situ within a medical device

Details Materials formable in situ within a medical device Materials formable in situ within a medical device

2010-12-16

2011-10-25

Bernshteyn, Michael M (Department: 1762)

Synthetic resins or natural rubbers -- part of the class 520 ser

Synthetic resins

At least one aryl ring which is part of a fused or bridged...

C606S192000, C623S001210, C623S926000

Reexamination Certificate

active

08044137

ABSTRACT:
Certain embodiments of the invention include forming a material in situ by introducing into a space within a patient a water soluble polymer precursor of at least about 10,000 molecular weight solubilized in a flowable aqueous solution. Functional groups on the polymer precursor undergo covalent bonding in situ to form a solid and nonbiodegradable material having a swellability less than about 20% v/v and a Young's modulus of at least about 100 kPa within about 30 seconds to about 30 minutes of initiating a chemical reaction of the functional groups to form the solid material.

REFERENCES:
patent: 3833003 (1974-09-01), Taricco
patent: 4311146 (1982-01-01), Wonder
patent: 4341218 (1982-07-01), Ü
patent: 4351922 (1982-09-01), Yoshida et al.
patent: 4490497 (1984-12-01), Evrard et al.
patent: 4641653 (1987-02-01), Rockey
patent: 4703108 (1987-10-01), Silver
patent: 4728328 (1988-03-01), Hughes et al.
patent: 4826945 (1989-05-01), Cohn et al.
patent: 4938763 (1990-07-01), Dunn et al.
patent: 5100992 (1992-03-01), Cohn et al.
patent: 5258042 (1993-11-01), Mehta
patent: 5266325 (1993-11-01), Kuzma et al.
patent: 5272012 (1993-12-01), Opolski
patent: 5376375 (1994-12-01), Rhee et al.
patent: 5410016 (1995-04-01), Hubbell et al.
patent: 5456693 (1995-10-01), Conston et al.
patent: 5462990 (1995-10-01), Hubbell et al.
patent: 5464396 (1995-11-01), Barta et al.
patent: 5510418 (1996-04-01), Rhee et al.
patent: 5514379 (1996-05-01), Weissleder et al.
patent: 5530528 (1996-06-01), Houki et al.
patent: 5534024 (1996-07-01), Rogers et al.
patent: 5583114 (1996-12-01), Barrows et al.
patent: 5587175 (1996-12-01), Viegas et al.
patent: 5603991 (1997-02-01), Kupiecki et al.
patent: 5624685 (1997-04-01), Takahashi et al.
patent: 5627233 (1997-05-01), Hubbell et al.
patent: 5629008 (1997-05-01), Lee
patent: 5660849 (1997-08-01), Polson et al.
patent: 5665117 (1997-09-01), Rhodes
patent: 5665840 (1997-09-01), Pohlmann et al.
patent: 5668236 (1997-09-01), Engelhardt et al.
patent: 5672662 (1997-09-01), Harris et al.
patent: 5690671 (1997-11-01), McGurk et al.
patent: 5693088 (1997-12-01), Lazarus
patent: 5714159 (1998-02-01), Shalaby
patent: 5752974 (1998-05-01), Rhee et al.
patent: 5769882 (1998-06-01), Fogarty et al.
patent: 5823198 (1998-10-01), Jones et al.
patent: 5824037 (1998-10-01), Fogarty et al.
patent: 5843160 (1998-12-01), Rhodes et al.
patent: 5851508 (1998-12-01), Greff et al.
patent: 5874500 (1999-02-01), Rhee et al.
patent: 5876448 (1999-03-01), Thompson et al.
patent: 5932462 (1999-08-01), Harris et al.
patent: 5962023 (1999-10-01), Jamiolkowski et al.
patent: 5994750 (1999-11-01), Yagi
patent: 6031148 (2000-02-01), Hayes et al.
patent: 6063061 (2000-05-01), Wallace et al.
patent: 6110198 (2000-08-01), Fogarty et al.
patent: 6129761 (2000-10-01), Hubbell
patent: 6152943 (2000-11-01), Sawhney
patent: 6168592 (2001-01-01), Kupiecki et al.
patent: 6190402 (2001-02-01), Horton et al.
patent: 6193745 (2001-02-01), Fogarety et al.
patent: 6196230 (2001-03-01), Hall et al.
patent: 6201065 (2001-03-01), Pathak et al.
patent: 6206930 (2001-03-01), Burg et al.
patent: 6251382 (2001-06-01), Greenwald et al.
patent: 6258870 (2001-07-01), Hubbell et al.
patent: 6261305 (2001-07-01), Marotta et al.
patent: 6261544 (2001-07-01), Coury et al.
patent: 6268405 (2001-07-01), Yao et al.
patent: 6271278 (2001-08-01), Park et al.
patent: 6283991 (2001-09-01), Cox et al.
patent: 6296603 (2001-10-01), Turnlund et al.
patent: 6299597 (2001-10-01), Buscemi et al.
patent: 6312462 (2001-11-01), McDermott et al.
patent: 6312463 (2001-11-01), Rourke et al.
patent: 6312725 (2001-11-01), Wallace et al.
patent: 6331184 (2001-12-01), Abrams
patent: 6334869 (2002-01-01), Leonhardt et al.
patent: 6371975 (2002-04-01), Cruise et al.
patent: 6379373 (2002-04-01), Sawhney et al.
patent: 6388047 (2002-05-01), Won et al.
patent: 6409757 (2002-06-01), Trout, III et al.
patent: 6458889 (2002-10-01), Trollsas et al.
patent: 6463317 (2002-10-01), Kucharczyk et al.
patent: 6495127 (2002-12-01), Wallace et al.
patent: 6506204 (2003-01-01), Mazzocchi
patent: 6514534 (2003-02-01), Sawhney
patent: 6517824 (2003-02-01), Kohn et al.
patent: 6534591 (2003-03-01), Rhee et al.
patent: 6544276 (2003-04-01), Azizi
patent: 6566406 (2003-05-01), Pathak et al.
patent: 6592614 (2003-07-01), Lenker et al.
patent: 6605294 (2003-08-01), Sawhney
patent: 6610033 (2003-08-01), Melanson et al.
patent: 6613037 (2003-09-01), Khosravi et al.
patent: 6632457 (2003-10-01), Sawhney
patent: 6639014 (2003-10-01), Pathak et al.
patent: 6656214 (2003-12-01), Fogarty et al.
patent: 6663607 (2003-12-01), Slaikeu et al.
patent: 6663667 (2003-12-01), Dehdashtian et al.
patent: 6673093 (2004-01-01), Sawhney
patent: 6703047 (2004-03-01), Sawhney et al.
patent: 6709668 (2004-03-01), Won et al.
patent: 6710126 (2004-03-01), Hirt et al.
patent: 6730119 (2004-05-01), Smalling
patent: 6818018 (2004-11-01), Sawhney
patent: 6827735 (2004-12-01), Greenberg
patent: 6843803 (2005-01-01), Ryan et al.
patent: 6887974 (2005-05-01), Pathak
patent: 6916857 (2005-07-01), Won et al.
patent: 6918926 (2005-07-01), Letort
patent: 6923986 (2005-08-01), Pathak et al.
patent: 6960227 (2005-11-01), Jones et al.
patent: 6962979 (2005-11-01), Rhee
patent: 7332566 (2008-02-01), Pathak et al.
patent: 2002/0026217 (2002-02-01), Baker et al.
patent: 2002/0045848 (2002-04-01), Jaafar et al.
patent: 2002/0052643 (2002-05-01), Wholey et al.
patent: 2003/0012734 (2003-01-01), Pathak et al.
patent: 2003/0014075 (2003-01-01), Rosenbluth et al.
patent: 2003/0036745 (2003-02-01), Khosravi et al.
patent: 2003/0051735 (2003-03-01), Pavcnik et al.
patent: 2003/0130725 (2003-07-01), DePalma et al.
patent: 2003/0135269 (2003-07-01), Swanstrom
patent: 2003/0204242 (2003-10-01), Zarins et al.
patent: 2003/0204249 (2003-10-01), Letort
patent: 2003/0216802 (2003-11-01), Chobotov et al.
patent: 2004/0016997 (2004-01-01), Ushio
patent: 2004/0044358 (2004-03-01), Khosravi et al.
patent: 2004/0082989 (2004-04-01), Cook et al.
patent: 2004/0098096 (2004-05-01), Eton
patent: 2004/0131582 (2004-07-01), Grinstaff et al.
patent: 2004/0204755 (2004-10-01), Robin
patent: 2005/0004660 (2005-01-01), Rosenbluth et al.
patent: 2005/0028484 (2005-02-01), Littlewood
patent: 2005/0065592 (2005-03-01), Holzer
patent: 2005/0169882 (2005-08-01), Lowe et al.
patent: 2005/0271727 (2005-12-01), Yao
patent: 2006/0025853 (2006-02-01), Evans et al.
patent: 2006/0258698 (2006-11-01), Mudumba et al.
patent: 2008/0033471 (2008-02-01), Paz et al.
patent: 0 732 109 (1996-09-01), None
patent: 1 704 878 (2006-09-01), None
patent: 1 967 220 (2008-09-01), None
patent: 98/12274 (1998-03-01), None
patent: 98/35631 (1998-08-01), None
patent: 99/03454 (1999-01-01), None
patent: 99/08718 (1999-02-01), None
patent: 99/22770 (1999-05-01), None
patent: 99/34833 (1999-07-01), None
patent: 99/59501 (1999-11-01), None
patent: 00/09199 (2000-02-01), None
patent: 00/12018 (2000-03-01), None
patent: 00/51522 (2000-09-01), None
patent: 01/21108 (2001-03-01), None
patent: 01/66038 (2001-09-01), None
patent: 02/102282 (2002-12-01), None
patent: 2006/078770 (2006-07-01), None
Gander et al., Crosslinked Poly(Alkylene Oxides) for the Preparation of Controlled Release Micromatrices, Journal of Controlled Release, 5:271-283 (1988).
Gayet et al., “High water content BSA-PEG hydrogel for controlled release device: Evaluation of the drug release properties”, Journal of Controlled Release, 38:177-184 (1996).
Kissel et al., “ABA-triblock copolymers from biodegradable polyster A-blocks and hydrophilic poly(ethyleen oxide) B-blocks as a candidate for in situ forming hydrogel delivery systems for proteins”, Advanced Drug Delivery Reviews, 54:99-134 (2002).
Sanabria-Delong et al., “Photo-Cross-Linked PLA-PEO-OLA Hydrogels from Self-Assembled Physical Networks: Mechanical Properties and Influence of Assumed Constitutive Relationships”, Biomacromolecules, 9:2784-2791 (2008).

Affiliated with

Also associated with

Rating

Materials formable in situ within a medical device does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Materials formable in situ within a medical device, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Materials formable in situ within a medical device will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-4295103