Materials for the production of nanometer structures and use the

Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues

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530300, 530324, 435 691, 435 697, C07K 1400, C12P 2106

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active

058640134

ABSTRACT:
The present invention pertains to nanostructures, i.e., nanometer sized structures useful in the construction of microscopic and macroscopic structures. In particular, the present invention pertains to nanostructures based on bacteriophage T4 tail fiber proteins and variants thereof.

REFERENCES:
Bella et al., 1994, "Crystal and molecular structure of a collagen-like peptide at 1.9.ANG. resolution", Science 226:75-81.
Earnshaw et al., 1979, "The distal half of the tail fibre of the bacteriophage T4 rigidly linked domains and cross-.beta. structure", J Mol Biol 132:101-131.
Edgar and Lielausis, 1965, "Serological studies with mutants of phage T4D defective in genes determining tail fiber structure", Genetics 52:1187-1200.
Freedman, 1991, "Exploiting the nanotechnology of life", Science 254(29):1308-1310.
Harbury et al., 1993, "A switch between two-, three-and four-standard coiled coils in GCN4 leucine zipper mutants", Science 262:1401-1407.
Henning et al., 1994, "Receptor recognition by T-even-type coliphages", in Molecular Biology of Bacteriophage T4, Karam (ed.), American Society of Microbiology, Washington, D.C. pp. 291-298.
Levy et al., 1980, "Region-specific recombination in phage T4. II. Structure of the recombinants", Genetics 94:531-547.
O'Shea et al., 1989, "Evidence that the leucine zipper is a coiled coil", Science 243:538-542.
Oliver and Crowther, 1981, "DNA Sequence of the tail fibre genes 36 and 37 of bacteriophage T4", J Mol Biol 153:545-568.
Seed, 1980, "Studies of the bacteriophage T4 proximal half tail fiber", Ph.D. Thesis (C.I.T.).
Steven et al., 1988, "Molecular substructure of a viral receptor-recognition proten: The gp17 tail fiber of bacteriophage T7", J Mol Biol 200:351-365.
Ward et al., 1970, "Assembly of bacteriophage T4 tail fibers II. Isolation and characterization of tail fiber precursors", J Mol Biol 54:15-31.
Whitesides et al., 1991, "Molecular self-assembly and nanochemistry: A chemical strategy for the synthesis of nanostructures"Science 254(29):1312-1318.
Wood et al., 1994, "Long tail fibers: Genes, proteins, structure and assembly", in Molecular Biology of Bacteriophage T4, Karam (ed.), American Society of Microbiology, Washington, D.C. pp. 282-290.

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