Organic compounds -- part of the class 532-570 series – Organic compounds – Amino nitrogen containing
Reexamination Certificate
2004-11-08
2009-10-06
Davis, Brian J (Department: 1621)
Organic compounds -- part of the class 532-570 series
Organic compounds
Amino nitrogen containing
C564S292000, C564S294000, C564S296000, C562S583000, C560S157000, C435S458000
Reexamination Certificate
active
07598421
ABSTRACT:
The invention provides a lipid of general formula (I) or (II):wherein X1, X2and R1to R5are as defined herein. Such lipids are used to form complexes with a biologically-active material such as a nucleic acid, peptide or small molecule for delivering the biologically-active material to cells. The complexes may incorporate an integrin-binding peptide and, when the biologically-active material is DNA, thereby constitute a LID complex.
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Hailes Helen C.
Hart Stephen L.
Hurley Christopher A.
Pilkington-Miksa Michael
Tabor Alethea B.
Clark & Elbing LLP
Davis Brian J
UCL Biomedica PLC
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