Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid
Reexamination Certificate
2008-01-15
2008-01-15
Lam, Ann Y. (Department: 1641)
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving nucleic acid
Reexamination Certificate
active
10516203
ABSTRACT:
Materials and method are disclose for delivering a desired substance to a target site, using a layered carrier in which the carrier and the substance together form at least three layers which associate by ionic interaction at the first pH, where at least one layer comprises a charge switch material which comprises an ionisable group and which has a positive charge at a first pH and a charge which is less positive, neutral or negative at a second pH, at least one layer comprises a polyionic polymer which is negatively charged at the first pH and at least one layer comprises the desired substance. Preferred carriers are based on the charge switch material poly Bis-Tris and the polyionic polymer polyacrylic acid.
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Baker Matthew J.
Cooper Paula
Harper Garry R.
Invitrogen Corporation
Lam Ann Y.
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