Chemistry: molecular biology and microbiology – Differentiated tissue or organ other than blood – per se – or...
Reexamination Certificate
2005-12-06
2005-12-06
Afremova, Vera (Department: 1651)
Chemistry: molecular biology and microbiology
Differentiated tissue or organ other than blood, per se, or...
C435S368000
Reexamination Certificate
active
06972168
ABSTRACT:
The subject invention pertains to compositions and methods for culturing nerve tissue in vitro and nerve grafts produced using such methods. The compositions and methods of the subject invention can be employed to restore the continuity of nerve interrupted by disease, traumatic events or surgical procedures. The invention also concerns methods for promoting repair of damaged nerve tissue using the present compositions and nerve tissue treated according to such methods.
REFERENCES:
patent: 4696816 (1987-09-01), Brown
patent: 4933185 (1990-06-01), Wheatley et al.
patent: 5231580 (1993-07-01), Cheung et al.
patent: 5292509 (1994-03-01), Hageman
patent: 5716617 (1998-02-01), Khandke et al.
patent: 5830468 (1998-11-01), Bini
patent: 5866120 (1999-02-01), Karageozian et al.
patent: 5916557 (1999-06-01), Berlowitz-Tarrant et al.
patent: 5997863 (1999-12-01), Zimmermann et al.
patent: 6033660 (2000-03-01), Mather et al.
patent: 6054569 (2000-04-01), Bennett et al.
patent: 6093563 (2000-07-01), Bennett et al.
patent: 6200564 (2001-03-01), Lamont et al.
patent: 6214978 (2001-04-01), Truog et al.
patent: 6231608 (2001-05-01), Stone
patent: 6267786 (2001-07-01), Stone
patent: 6448076 (2002-09-01), Dennis et al.
patent: 6455309 (2002-09-01), Stone
patent: 2001/0034043 (2001-10-01), Su et al.
patent: 2001/0039459 (2001-11-01), Stone
patent: 2003/0068815 (2003-04-01), Stone et al.
patent: 2003/0072749 (2003-04-01), Muir
patent: 2003/0077258 (2003-04-01), Muir
patent: 19530556 (1996-09-01), None
patent: 0 576 294 (1993-12-01), None
patent: 0 613 949 (1994-09-01), None
patent: 0 776 968 (1997-06-01), None
patent: 0 875 253 (1998-11-01), None
patent: WO 91/06303 (1991-05-01), None
patent: WO 91/06573 (1991-05-01), None
patent: WO 01/35977 (2001-05-01), None
patent: WO 01/39795 (2001-06-01), None
patent: 2003/015612 (2003-02-01), None
Evans et al. Progress in Neurobiology, 1994. vol. 43, pp. 187-233.
Lassner et al. Journal of Reconstructive Microsurgery. Nov. 1995. vol. 11, No. 6, pp. 447-453.
Ferguson et al. Molecular and Cellular Neuroscience. 2000. 16: 157-167.
Krekoski, C.A. et al. “Metalloproteinase-Dependent Predegeneration In Vitro Enhances Axonal Regeneration within Acellular Peripheral Nerve Grafts”J. Neuroscience, Dec. 2002, 22(23):10408-10415.
Lemons, M.L. et al. “Chondroitin Sulfate Proteoglycan Immunoreactivity Increases Following Spinal Cord Injury and Transplantation”Exper. Neuro., 1999, 160:51-65.
McKeon, R.J. et al. “Reduction of Neurite Outgrowth in a Model of Glial Scarring following CNS Injury is Correlated with the Expression of Inhibitory Molecules on Reactive Astrocytes”J. Neurosci., 1991, 11(11):3398-3411.
McKeon, R.J. et al. “Injury-Induced Proteoglycans Inhibit the Potential for Laminin-Mediated Axon Growth on Astrocytic Scars”Exp. Neuro., 1995, 136:32-43.
Yick, L-W. et al. “Chondroitinase ABC promotes axonal regeneration of Clarke's neurons after spinal cord injury”NeuroReport, 2000, 11(5):1063-1067.
Jones, L.L. et al. “Neurotrophic factors, cellular bridges and gene therapy for spinal cord injury”J. Physiology, 2001, 533. 1:83-89.
Smith-Thomas, L.C. et al. “Increased axon regeneration in astrocytes grown in the presence of proteoglycan synthesis inhibitors”J. Cell Sci., 1995, 108:1307-1315.
Smith-Thomas, L.C. et al. “An inhibitor of neurite outgrowth produced by astrocytes”J. Cell Sci., 1994 107:1687-1695.
Bradbury, E.J. et al. “Chondroitinase ABC promotes functional recovery after spinal cord injury”Nature, Apr. 2002, 416(6881):636-640.
Muir, D. et al. “Schwannoma Cell-derived Inhibitor of the Neurite-promoting activity of Laminin”J. Cell Biol., Nov. 1989, 109:2353-2362.
Bennett, G.S. et al. “Chondroitinase ABC delivered to the site of a spinal cord injury upregulates GAP-43 expression in dorsal root ganglion neurons”Society for Neuroscience Abstracts, 2000, 26(1-2):Abstract No. 324.3 from 30thAnnual Meeting of the Society of Neuroscience, presented Nov., 2000; mailed to subscribers Sep., 2000.
Schmalfeldt et al., “Brain Derived Versican V2 is a Potent Inhibitor of Axonal Growth,”Journal of Cell Science113: 807-816 (2000).
Braunewell, K-H. et al. “Functional Involvement of Sciatic Nerve-derived Versican- and Decorin-like Molecules and other Chondroitin Sulphate Proteoglycans in ECM-mediated Cell Adhesion and Neurite Outgrowth”Euro. J. Neurosci., 1995, 7:805-814.
Braunewell, K-H. et al. “Up-regulation of a Chondroitin Sulphate Eptiope during Regeneration of Mouse Sciatic Nerve: Evidence that the Immunoreactive Molecules are Related to the Chondroitin Sulphate Proteogylcans Decorin and Versican”Eur J. Neurosci, 1995, 7:792-804.
Brown, M.C. et al. “Further Studies on Motor and Sensory Nerve Regeneration in Mice With Delayed Wallerian Degeneration”Eur J Neurosci, 1994, 6:420-428.
Evans, P.J. et al. “Regeneration Across Cold Preserved Peripheral Nerve Allografts”Microsurgery, 1999, 19:115-127.
Hasan, N. et al. “The influence of predegenerated nerve grafts on axonal regeneration from prelesioned peripheral nerves”J Anat, 1996, 189:293-302.
Lassner, F. et al. “Preservation of Peripheral Nerve Grafts: A Comparison of Normal Saline, HTK Organ Preservation Solution, and DMEM Schwann Cell Culture Medium”J Reconstr Microsurg, 1995, 11:447-453.
Nadim, W. et al. “The role of Schwann cells and basal lamina tubes in the regeneration of axons through long lengths of freeze-killed nerve grafts”Neuropathol Appl Neurobiol, 1990, 16:411-421.
Stoll, G. and H.W. Müller “Nerve Injury, Axonal Degeneration and Neural Regeneration: Basic Insights”Brain Pathology, 1999, 9:313-325.
Agius, E. and P. Cochard “Comparison of Neurite Outgrowth Induced by Intact and Injured Sciatic Nerves: A Confocal and Functional Analysis”The Journal of Neuroscience, Jan. 1, 1998, 18(1):328-338.
Bertolotto, A. et al. “Immunohistochemical Localizationof Chondroitin Sulfate in Normal and Pathological Human Muscle”J Neurol Sci, 1986, 73:233-244.
Bradbury, E.J. et al. “Chondroitinase ABC Delivered to the Site of a Spinal Cord Injury Upregulates GAP-43 Expression in Dorsal Root Ganglion Neurons”Soc. Neurosci Abstr, Nov. 2000, abstract presented at the 30thAnnual Meeting of the Society of Neuroscience.
Danielsen, N. et al. “Predegeneration enhances regeneration into acellular nerve grafts”Brain Res, 1995, 681:105-108.
Danielsen, N. et al. “Pre-degenerated nerve grafts enhance regeneration by shortening the initial delay period”Brain Res, 1994, 666:250-254.
Evans, P.J. et al. “The Peripheral Nerve Allograft: A Comprehensive Review of Regeneration and Neuroimmunology”Prog Neurobiol, 1994, 43:187-233.
Evans, P.J. et al. “Cold Preserved Nerve Allografts: Changes in Basement Membrane, Viability, Immunogenicity, and Regeneration”Muscle Nerve, Nov. 1998, 21:1507-1522.
Fawcett, J.W. and R.J. Keynes “Peripheral Nerve Regeneration”Annu Rev Neurosci, 1990, 13:43-60.
Ferguson, T.A. and D. Muir “MMP-2 and MMP-9 Increase the Neurite-Promoting Potential of Schwann Cell Basal Laminae and Are Upregulated in Degenerated Nerve”Mol Cell Neurosci, 2000 16:157-167.
Fu, S.Y. and T. Gordon “The Cellular and Molecular Basis of Peripheral Nerve Regeneration”Mol Neurobiol, 1997, 14(1):67-116.
Giannini, C. and P. Dyck “The Fate of Schwann Cell Basement Membranes in Permanently Transected Nerves”J Neuropathol Exp Neurol, 1990 49(6):550-563.
Gordon, L. et al. “Predegenerated nerve autografts as compared with fresh nerve autografts in freshly cut and precut motor nerve defects in the rat”J Hand Surg[Am], Jan. 1979, 4(1):42-47.
Gulati, A.K. “Evaluation of acellular and cellular nerve grafts in repair of rat peripheral nerve”J Neurosug, Jan. 1988, 68:117-123.
Ide, C. et al. “Schwann Cell
Afremova Vera
Goodwin & Procter LLP
University of Florida Research Foundation Incorporated
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