Materials and methods for isolating IgA immunoglobulins

Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Separation or purification

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530412, C07K 122

Patent

active

060751282

ABSTRACT:
The subject invention concerns novel polynucleotide sequences which code for polypeptides which bind IgA. A further aspect of the invention are hybrid proteins (and genes encoding these hybrid proteins) which comprise binding domains for both IgA and IgG.

REFERENCES:
patent: 4757134 (1988-07-01), Blake et al.
patent: 4876194 (1989-10-01), Bjorck et al.
patent: 5413918 (1995-05-01), Faulmann
patent: 5644030 (1997-07-01), Faulmann
patent: 5714334 (1998-02-01), Faulmann
Boyer, K.M., Gotoff, S.P. (1986) "Prevention of Early-Onset Neonatal Group B Streptococcal Disease with Selective Intrapartum Chemoprophylaxis" New England J. Med. 314: 1665-1669.
Brady, L.J., Boyle, M.D.P. (1989) "Identification of Non-Immunoglobulin A-Fc-Binding Forms and Low-Molecular-Weight Secreted Forms of the Group B Streptococcal .beta. Antigen" Infect. Immun. 57: 1573-1581.
Bunn-Moreno, M.M. Campos-Neto, A. (1981) "Lectin(s) Extracted from Seeds of Artocarpus integrifolia (Jackfruit): Potent and Selective Stimulator(s) of Distinct Human T and B Cell Functions" J. Immunol. 127: 427-429.
Christensen, P., Oxelius, V.A. (1975) "A Reaction Between Some Streptococci and IgA Myeloma Proteins" Acta Path. Microbial. Scand. Sect. C. 83: 184.
Cleat, P.H., Timmis, K.N. (1987) "Cloning and Expression in Escherichia coli of the Ibc Protein Genes of Group B Streptococci: Binding of Human Immunoglobulin A to the Beta Antigen" Infect. Immun. 55(5): 1151-1155.
Heden, L. et al. (1991) "Molecular characterization of an IgA receptor from group B streptococci: Sequence of the gene, identification of a proline-rich region with unique structure and isolation of N-terminal fragments with IgA-binding capacity" Eur. J. Immunol. 21: 1481-1490, (sequence only).
Jelinkova, J. (1977) "Group B Streptococci in the Human Population" Current Topics in Microbiology and Immunology. 127(2): 427-429.
Kondoh, H. et al. (1986) "Jacalin, a jackfruit lectin, precipitates IgA1 but not IgA2 subclass on gel diffusion reaction" Journal of Immunological Methods 88: 171-173.
Lim, D.V., Morales, W.J., Walsh, A.F., Kazanis, D. (1986) "Reduction of Morbidity and Mortality Rates for Neonatal Group B Streptococcal Disease through Early Diagnosis and Chemoprophylaxis" J. Clin. Micro. 23(3): 489-492.
Lindahl, G. et al. (1990) "Characterization of an IgA Receptor from Group B Streptococci: Specificity for serum IgA" Eur. J. Immunol. 20: 2241-2247.
Russell-Jones, G.J. et al. (1984) "A Surface Receptor Specific for Human IgA on Group B Streptococci Possessing the Ibc Protein Antigen" J. Exp. Med. 160: 1467-1475.
Russell-Jones, G.J., Gotschlich, E.C. (1984) "Identification of Protein Antigens of Group B Streptococci, with Special Reference to the Ibc Antigens" J. Exp. Med. 160: 1476-1484.

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