Materials and methods for detection and characterization of...

Details Materials and methods for detection and characterization of... Materials and methods for detection and characterization of...

2006-05-23

2006-05-23

Goldberg, Jeanine A. (Department: 1634)

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving nucleic acid

C435S091100, C435S091200, C536S023100

Reexamination Certificate

active

07049070

ABSTRACT:
A method for influencing the separation mobility of single stranded nucleic acids in native conditions is disclosed. Temperature changes during the separation of single stranded nucleic acids under native conditions are used as the basis of a novel method of detection of specific nucleic acid sequences.

REFERENCES:
patent: 6153811 (2000-11-01), Lowe et al.
patent: 6287441 (2001-09-01), Liu et al.
Chen et al. (Nucleic acids Research, vol. 23, No. 21, pp. 4524-4525, 1995).
Sugano et al. (Electrophoresis, vol. 16, pp. 8-10, 1995).
Rubben et al. (Eur. J. of Epidemiology, vol. 11, pp. 501-506 1995).
Wallace (Laboratory methods for the detection of mutations and polymorphisms in DNA, 2000, pp. 79-94).

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