Materials and method for the detection and treatment of Wegener'

Details Materials and method for the detection and treatment of Wegener' Materials and method for the detection and treatment of Wegener'

1997-10-17

2000-03-07

Chan, Christina Y.

Chemistry: analytical and immunological testing

For preexisting immune complex or auto-immune disease

Immune complex

435 71, 435 792, 530327, G01N 33564

Patent

active

060339152

ABSTRACT:
The subject invention pertains to the identification of peptides useful in the detection and treatment of Wegener's granulomatosis.

REFERENCES:
Blockmans et al. Annals of the Rheumatic Diseases, vol. 57:141-145 1998.
Williams, Jr., Ralph C., Roland Staud, Christine C. Malone, Joel Payabyab, Laura Byres, Dennis Underwood (1994) "Epitopes on Proteinase-3 Recognized by Antibodies from Patients with Wegener's Granulomatosis" Journal of Immunology 152:4722-4737.
Campanelli, David, Maxine Melchior, Yiping Fu, Munehiro Nakata, Howard Shuman, Carl Nathan, and Joelle E. Gabay (1990) "Cloning of cDNA for Proteinase 3: A Serine Protease, Antibiotic, and Autoantigen from Human Neutrophils" J. Exp. Med. 172:1709-1715.

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