Mast cell protease peptide inhibitors

Details Mast cell protease peptide inhibitors Mast cell protease peptide inhibitors

1998-01-30

1999-09-21

Tsang, Cecilia J.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

514 18, 530329, 530330, 530331, A61K 3804, A61K 3805, A61K 3808

Patent

active

059554312

ABSTRACT:
Compositions and methods for inhibiting a complex containing a mast cell protease are provided. The compositions are useful for treating inflammatory disorders, such as asthma, that are mediated by release of a tryptase-6 protein. Methods for identifying additional specific inhibitors of a complex containing tryptase-6 protein and a serglycin glycosaminoglycan also are provided.

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