Mass spectrometry precursor ion selection

Chemistry: analytical and immunological testing – Nuclear magnetic resonance – electron spin resonance or other...

Reexamination Certificate

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C436S086000, C702S019000, C250S281000, C250S282000

Reexamination Certificate

active

07998750

ABSTRACT:
The present invention is concerned with methods for the selection of precursor ions of a sample polypeptide for fragmentation in mass spectrometry, together with methods for determining at least one putative amino acid sequence for a sample polypeptide, apparatus and computer programs for same.

REFERENCES:
patent: 03102572 (2003-12-01), None
Anderson et al.: “A new Algorithm for the evaluation of shotgun peptide sequencing in proteomics: Support vector machine classification of peptide MS/MS spectra and SEQUEST scores.”, Journal of Proteome Research, vol. 2, No. 2, 2003, pp. 137-146.
Papayannopoulos I A: “The Interpretation of Collision-Induced Dissocation Tandem Mass Spectra of Peptides”, Mass Spectrometry Reviews, John Wiley and Sons, New York, NY, US, vol. 14, 1995, pp. 49-73.
Jensen O N et al.: “Automation of matrix-assisted laser desorption/ionization mass spectrometry using fuzzy logic feedback control.” Analytical Chemistry. May 1, 1997, vol. 69, No. 9, pp. 1706-1714.

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